"विटामिन बी१२": अवतरणों में अंतर
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अनुनाद सिंह (वार्ता | योगदान) |
अनुनाद सिंह (वार्ता | योगदान) No edit summary |
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पंक्ति 1:
{{Drugbox
[[File:Cobalamin skeletal.svg|thumb]]▼
| drug_name = विटामिन B<sub>12</sub><br />(data for cyanocobalamin)
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 477163311
| IUPAC_name = α-(5,6-Dimethylbenzimidazolyl)cobamidcyanide
| width = 200
| caption = [[Skeletal formula]] of a generic cobalamin
| image2 = Cyanocobalamin-from-xtal-3D-st-noH.png
| width2 =
| alt2 =
| caption2 = [[Ball-and-stick model|Stick model]] of [[cyanocobalamin]] (R = CN) based on the crystal structure<ref>{{ cite journal | title = Inorganic Cyanide as Protecting Group in the Stereospecific Reconstitution of Vitamin B<sub>12</sub> from an Artificial Green Secocorrinoid | authors = Lucas Prieto, Markus Neuburger, Bernhard Spingler, Felix Zelder | journal = [[Organic Letters|Org. Lett.]] | year = 2016 | volume = 18 | issue = 20 | pages = 5292–5295 | doi = 10.1021/acs.orglett.6b02611 | pmid = 27726382 | url = https://pubs.acs.org/doi/10.1021/acs.orglett.6b02611 }}</ref>
<!--Clinical data-->
| synonyms = Vitamin B12, vitamin B-12, cobalamin
| tradename =
| Drugs.com = {{drugs.com|monograph|vitamin_b12}}
| MedlinePlus = a605007
| DailyMedID = Vitamin_b12
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US = <!-- A / B / C / D / X -->
| legal_AU = <!-- Unscheduled / S2 / S4 / S8 -->
| legal_UK = POM
| legal_US = OTC
| routes_of_administration = [[Oral administration|By mouth]], sublingual, [[intravenous]] (IV), [[intramuscular]] (IM), intranasal
<!--Pharmacokinetic data-->
| bioavailability = Readily absorbed in distal half of the ileum.
| protein_bound = Very high to specific [[transcobalamins]] plasma proteins.<br />Binding of [[hydroxocobalamin]] is slightly higher than cyanocobalamin.
| metabolism = [[liver]]
| elimination_half-life = Approximately 6 days<br />(400 days in the liver).
| excretion = [[kidney]]
<!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 68-19-9
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = P6YC3EG204
| ATC_prefix = B03
| ATC_suffix = BA01
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72–42)32(4)54(59)73–56;1–2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;;+2/p-2/t31?,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+;;/m1../s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = RMRCNWBMXRMIRW-WYVZQNDMSA-L
| PubChem = 184933
| DrugBank_Ref = {{drugbankcite|changed|drugbank}}
| DrugBank = DB00115
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 10469504
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D00166
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 2110563
<!--Chemical data-->
| C=63 | H=88 | Co=1 | N=14 | O=14 | P=1
| smiles = NC(=O)C[C@@]8(C)[C@H](CCC(N)=O)C=2/N=C8/C(/C)=C1/[C@@H](CCC(N)=O)[C@](C)(CC(N)=O)[C@@](C)(N1[Co+]C#N)[C@@H]7/N=C(C(\C)=C3/N=C(/C=2)C(C)(C)[C@@H]3CCC(N)=O)[C@](C)(CCC(=O)NCC(C)OP([O-])(=O)O[C@@H]6[C@@H](CO)O[C@H](n5cnc4cc(C)c(C)cc45)[C@@H]6O)[C@H]7CC(N)=O
}}
शरीर को स्वस्थ रखने के लिए पर्याप्त मात्रा में विभिन विटामिन्स, मिनरल्स, प्रोटीन्स, कार्बोहाइड्रेट्स और फाइबर इत्यादि की आवश्यकता होती हैं। शरीर के लिए ज्यादातर आवश्यक तत्वों का पोषण आहार पदार्थो से हो जाता हैं। एक विटामिन ऐसा है जो शरीर के स्वास्थ्य के लिए बेहद जरुरी है परन्तु आहार तत्वों में वह पर्याप्त मात्रा में उपलब्ध न होने से ज्यादातर भारतीय लोगो में इस विटामिन की कमी पायी जाती हैं। इस विटामिन का नाम हैं - विटामिन B12
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